Can You Mix Protein Powder With Creatine?

Can You Mix Protein Powder With Creatine?

Creatine and protein powder are two of the most popular supplements you can take to build more muscle, get stronger, and optimize your gym performance.

The question is, can you mix protein powder with creatine, or might it be better to take the two supplements separately? 

Let’s discuss.

Can You Mix Protein Powder With Creatine?

Mixing protein powder with creatine is entirely safe, and there is no real reason to take the two at different times. 

The two supplements have been studied extensively, and their effects on the body are clear. 

Protein powder supplements supply a concentrated dose of protein, which the body breaks down, and extracts amino acids. These building blocks are necessary for muscle repair, physical development, the production of various organic components (hormones, enzymes, antibodies, etc.), and overall health. 

Creatine is an organic acid that boosts your athletic performance by supporting energy production. The majority of creatine is stored in skeletal muscle as creatine phosphate. It supports the production of adenosine triphosphate molecules (ATP)––the primary energy currency for all living cells.

ATP demands can increase as much as 1,000-fold during exercise, so having more creatine in your muscles allows your body to synthesize new molecules quickly. As a result, you can train harder and longer before getting tired.

Protein With Creatine Powder

Would Protein Powder and Creatine Work Better If Taken Separately?

Creatine and protein powder might work together, but do they function optimally, or might it be better to take the two products a few hours apart?

No, taking creatine and protein powder separately doesn’t offer any benefits. In fact, taking the two supplements together might bring some extra benefits. (1)

Consuming protein with creatine can lead to slightly better creatine absorption, leading to quicker muscle saturation and more pronounced benefits once you start supplementation. Some data suggests that protein can help you absorb up to 25 percent more creatine. (2)

Potential Benefits of Taking Protein Powder With Creatine

1. Superior Absorption

As discussed in the previous point, taking the two supplements together can result in slightly better creatine absorption. As a result, muscle creatine levels can increase more rapidly, allowing you to achieve saturation in less time.

You can also maintain saturation with less creatine (e.g., three grams daily instead of five).

2. Lower Risk of GI Issues

Creatine is one of the best-studied supplements, and numerous studies display its safety. The only potential issues reported by some individuals are nausea, bloating, and similar. 

The good news is that taking your creatine with some food or protein powder can reduce the risk of GI issues.

3. Superior Consistency

Creatine and protein powder are linked to superior strength gains and muscle growth when combined with a solid resistance training program. 

Taking the two products together might not necessarily lead to more strength or muscle mass, but it can help you stay more consistent with your intake, which is undoubtedly beneficial in the long run.

The Bottom Line

So, can you mix protein powder with creatine? Absolutely. In fact, there are several good reasons why taking them together is a good idea.

Of course, you can also take them separately if that works better. Don’t worry too much about the timing; focus on being consistent. Consistency always wins the day, because a high majority give up in their fit quest.

And you can click to learn the difference between creatine and protein powder.

A Few Additional Items Related to Creatine

CRN-5 Best Creatine PowderAnd if you’re looking to build lean muscle and optimize your efforts, check our review for the most effective creatine powder for building lean muscle. And also make sure you know the best time to take creatine. The more info and knowledge that you have, the more you’ll optimize your efforts.

Another consideration is creatine pills vs powder. One of the two provides quicker benefits. As well as the different types of creatine, and which one is best for you to provide maximum results.

And lastly, should creatine be taken as a pre-workout? Find out the answer here.

Click to return to all supplements.

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Philip Stefanov

Philip is a fitness writer, blogger, certified personal trainer, and the founder of He has spent the last nine years writing fitness content and training men and women in the gym, as well as online. His passion is fitness and exercise, and helping others improve their fitness and wellness.

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  1. Preiato, D. (2019, August 12). Creatine and whey protein: Should you take both? Healthline.
  2. Cooper, R., Naclerio, F., Allgrove, J., & Jimenez, A. (2012, July 20). Creatine supplementation with specific view to exercise/sports performance: An update. Journal of the International Society of Sports Nutrition.

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